When a child regularly feels down and does not exhibit any desire in playing or going to school, it may be indications of Chronic Fatigue Syndrome (CFS). This is a complex illness characterized by severe fatigue and is not improved by bed rest. It may even be worsened by strenuous physical activities or extreme mental exertion. Children with CFS generally functioned at a much lower degree of strength even before the onset of the disease. A child suffering from CFS may also show signs of general weakness, muscle pain, weak memory or poor mental focus, sleep problems, and post-exertion fatigue that lasts for over 24 hours.

To better understand this mysterious illness that afflicts thousands if not millions of children all over the world, a team of researchers conducted an investigation to determine the connection between what causes fatigue to stress and emotional abuse. Based on the U.S. Centers for Disease Control (CDC), childhood trauma rises the child or adults' risk of Chronic Fatigue Syndrome by three to eightfold. Another study based on the data from the Swedish Twin Registry shows that stress is a triggering factor for the said fatigue syndrome. The research in addition shows that emotional insecurity is a significant CFS risk factor, even if genetic and family factors also determine whether this personality trait will cause excessive and normal fatigue. Researchers from CDC agree with the hypothesis that CFS represents a disorder of adaptation which is promoted by early environmental factors which include malnutrition and emotional support which, later on, leads to failure to properly respond to physical, mental, and emotional challenges.

Different studies conducted on more than 19,000 twins born in Sweden observed that emotional instability was linked to a 72% greater risk of CFS symptoms. Emotional instability is a personality trait and tends to result in poor self-esteem and feelings of anxiety, depression, and guilt. Conclusively, emotional instability is a significant risk factor for CFS, whether a person with this personality trait really gets CFS depends on unknown genetic and family factors. Therefore, emotional instability is an indirect cause for CFS, while stress is a direct risk factor.

The greatest problem that researchers deal with is that there are still no drugs that provide complete and permanent cures for fatigue. CFS still remains a disease that is largely not understood. The problem is that there are simply countless causes of extreme fatigue. Despite that, step by step modern medicine is dealing with the many causes and finds methods of reducing - and at times even curing - this horrible disorder.

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